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If priapism is not treated immediately, penile tissue damage and permanent loss of potency may result.
Levitra should be used with caution by patients with anatomical cialis 8 x 20 mg deformation of the penis (such as angulation, cavernosal fibrosis, or Peyronies disease) or by patients who cialis 8 x 20 mg have conditions that may predispose them to priapism (such cialis 8 x 20 mg as sickle cell anemia, multiple myeloma, or leukemia). Physicians should advise cialis 8 x 20 mg patients to stop use of all phosphodiesterase type 5 (PDE5) inhibitors, including Levitra, and seek medical attention in the event of sudden loss of vision in one or both eyes. Such an event may be a sign of non-arteritic anterior ischemic optic neuropathy (NAION), a rare condition and a cause of decreased vision, including permanent loss of vision, that has been reported rarely postmarketing in temporal association with the use of all PDE5 inhibitors. An observational case-crossover study evaluated the cialis 8 x 20 mg risk of NAION when PDE5 inhibitor use, as a class, occurred immediately before NAION onset (within 5 half-lives), cialis 8 x 20 mg compared to PDE5 inhibitor use in a prior time period. Other risk factors for NAION, such as the presence of «crowded» optic disc, may have contributed to the occurrence of NAION in these studies.
Neither the rare postmarketing reports, nor the association of PDE5 inhibitor use cialis 8 x 20 mg and NAION sildenafil last how long in the observational studies, substantiate a causal relationship between PDE5 inhibitor use and NAION see Adverse Reactions 6.2.