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At the end of the infusion, plasma concentrations declined in a biphasic manner. All subjects had very low, albeit detectable plasma concentrations of sildenafil at 24 h (1 ng levitra 10 mg durata effetto ml −1) and 32 h (0.3 ng ml −1) after receiving the drug, compared with a peak plasma concentration of 531 ng ml −1. Plasma concentrations then declined in a biphasic manner with a mean terminal half-life of 4.1h Ten of 12 subjects had barely detectable plasma concentrations of sildenafil at 24 h (0.8 ng ml −1) and 32 h (0.3 ng ml −1) after receiving the drug, compared with a peak plasma concentration of 159 ng ml −1. Geometric mean data are presented for AUC, AUC t and C max, arithmetic means are presented for t max, k el, CL, V and V ss, and harmonic means are presented for t 1/2. The levitra 10 mg durata effetto pharmacokinetic parameters of sildenafil and UK-103,320 are summarized levitra 10 mg durata effetto levitra 10 mg durata effetto in Table levitra 10 mg durata effetto 2. The levitra 10 mg durata effetto data for UK-103,320 were similar to those of sildenafil, in fasting subjects, AUC and C max were both higher and t max was shorter than in fed subjects.