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Viagra made by Pfizer and Cialis by Eli Lilly are phosphodiesterase type 5 (PDE5) inhibitors which break down cyclic guanosine monophosphate (cGMP). In a gross simplification, after sexual stimulation, an erection occurs through the release of nitric oxide (NO) which causes dilation of blood vessels due to an accumulation of (cGMP).
Dysfunction occurs when cGMP conflicts with the NO vasodilatory effects.
When the PDE5 inhibitor is introduced, the cGMP is broken down. For example, Viagra is made with sildenafil and has viagra side effects vision a wait time of 30–60 minutes lasting for up to 4 hours. Cialis main ingredient is tadalafil and can either be taken daily (meaning it is always viagra side effects vision active in the body) or 30 minutes to 12 hours viagra side effects vision before activity to last up to 36 hours. This longer lasting formula is one viagra side effects vision of the benefits over the «little blue viagra side effects vision pill» which has proved to be more appealing to most men.
Further, sildenafil and tadalafil have viagra side effects vision different chemical and molecular structures.